background according to the previous studies, antihypertensive drugs should be withdrawn before surgery. nowadays it is accepted that some drugs effectively control systemic blood pressure (bp) to assure its desirable therapeutic control. objectives in this study, the effects of captopril, an angiotensin converting enzyme inhibitor (acei), on hemodynamic changes before, during and after the cor...

background: alcohol is a substance that is consumed widely around the world. there are different interpretations regarding the effects of alcohol on athletic performance. today, alcohol is introduced as a contributing factor for increasing athletic performance by some sport clubs. methods: the purpose of this article is to investigate the effects of alcohol on athletic performance. pubmed, scop...

The current status of the use of vasodilator drugs in the treatment of acute and chronic heart failure has been reviewed. It is apparent that vasodilator treatment can be used effectively in some patients with heart failure with a beneficial haemodynamics response, and that vasodilator agents are likely to find an important place in the management of such patients. Vasodilator treatment may be ...

Epoprostenol sodium (prostacyclin) administered intravenously is considered the standard for assessing the ability of the pulmonary circulation to vasodilate. At present, epoprostenol sodium is an investigational drug that has limited availability. In contrast, acetylcholine, also a pulmonary vasodilator, is readily available. Therefore, we assessed the feasibility of using acetylcholine as an ...

a pulmonary vasodilator, is readily available. Therefore, we assessed the feasibility of using acetylcholine as an alternative to prostacyclin in testing for the capacity of the pulmonary vasculature to vasodilate. Twenty-three patients with primary pulmonary hypertension (mean pulmonary arterial pressure, 58.5±13.4 mm Hg) received incremental infusions of prostacyclin and acetylcholine to pred...

Background: Alcohol is a substance that is consumed widely around the world. There are different interpretations regarding the effects of alcohol on athletic performance. Today, alcohol is introduced as a contributing factor for increasing athletic performance by some sport clubs. Methods: The purpose of this article is to investigate the effects of alcohol on athletic performance. PubMed, Scop...

The effects of 1H-[1,2,4]-oxadizaolo[4,3-]quinoxaline-1-one (ODQ), an inhibitor of the activation of soluble guanylate cyclase (sGC) on responses to NO donors acetylcholine (ACh) and bradykinin (BK) were investigated in the pulmonary and systemic vascular beds of the rat. In these studies the administration of ODQ in a dose of 5 mg/kg iv attenuated vasodilator responses to five different NO don...